Vasculitis Gives Higher Risk for Adverse Pregnancy Outcomes
Pregnancy in patients with vasculitis had a higher risk for preterm delivery and preeclampsia/eclampsia — especially those with small-vessel vasculitis — compared with the general obstetric population, in a large analysis of administrative claims data presented at the American College of Rheumatology (ACR) 2023 Annual Meeting.
"We suspect that there is a relationship between the increased risk of these serious hypertensive disorders and preterm delivery, given the higher risk of medically indicated preterm delivery," one the of the study authors, Audra Horomanski, MD, said in an interview prior to her presentation in a plenary session at the meeting.
Limited data exists on the risks of pregnancy in patients with systemic vasculitis, according to Horomanski, a rheumatologist who directs the Stanford Vasculitis Clinic at Stanford University in California. "The majority of what we do know comes from relatively small cohort studies," she said. "This is the first US, nationwide database study looking at the risk of preterm delivery and other adverse pregnancy outcomes."