Rapidly, Fully Optimize HF Meds After Hospital Discharge: STRONG-HF
Clinicians who prescribe heart failure meds are holding the best hand they've ever had, but with so much underuse and suboptimal dosing in actual practice, it seems many may not appreciate the value of their cards. But a major randomized trial that has captured the field's attention may embolden them to go all in.
Results showed that a strategy of early, rapid uptitration of multiple guideline-directed meds in patients hospitalized with heart failure, compared with a usual-care approach, cut their 6-month risk for death or HF readmission by a steep 34% (P = .002).
The drugs had been started and partly uptitrated in the hospital with the goal of full uptitration within 2 weeks after discharge.