Medisch  >  Genetic Susceptibility to COVID-19 Linked to Hypothyroidism

Genetic Susceptibility to COVID-19 Linked to Hypothyroidism

02/08 - A novel study of genome-wide association studies (GWASs) of people with COVID-19 or thyroid disorders shows that having COVID-19, or even just a genetic susceptibility for infection with the virus, increases the risk of developing hypothyroidism in a causative manner.

"To our knowledge, this is the first Mendelian randomization study evaluating the causal relationship between host genetic liability to COVID-19 phenotypes and thyroid-related traits," the authors write.

The results show that "host genetic susceptibility to SARS-CoV-2 infection is associated with increased risk of overt and subclinical hypothyroidism," senior author Ching-Lung Cheung, PhD, an associate professor in the Department of Pharmacology and Pharmacy, the University of Hong Kong, Pokfulam, Hong Kong, told Medscape Medical News.

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